FU-MING ZHOU, Ph.D.

Associate Professor

Department of Pharmacology

The University of Tennessee College of Medicine

Address

The University of Tennessee Health Science Center

874 Union Avenue

Memphis, TN 38163

Tel: (901) 448-1779;

Lab: 315 Crowe Building

Education

Ph.D. Institution: Department of Physiology and Biophysics, University of Alabama at Birmingham

Postdoctoral: Department of Neurobiology, University of Alabama at Birmingham

Research Interests

Dr. Zhou currently conducts a multidisciplinary research program designed to determine the molecular, cellular and neuropharmacological mechanisms of the brain monoamine systems. Particular attention is being paid to the contributions of these monoamine systems to neuropsychiatric disorders such as Alzheimer's disease, Parkinson‚s disease, depression, schizophrenia, drug abuse, and attention deficit hyperactivity disorder (ADHD). We use rodents as our experimental animals. Mutant and transgenic mice are also used.

Several techniques are used in the laboratory:

1. Electrophysiology-patch clamp
2. Single cell RT-PCR (in combination with patch clamp)
3. Electrochemistry (fast cyclic voltammetry at the carbon fiber microelectrode; HPLC)
4. Immunohistochemistry and confocal microscopy

Funding

Dr. Zhou’s research is funded by R01 grants from the National Institute on Drug Abuse and National Institute of Mental Health and grants from private foundations.

Employment

To apply for a job in Dr. Zhou’s lab, please email him your CV. Patch clamp and/or molecular biology skills are required.

Recent Publications

• Zhou FM, Li Z, Fan L, Zhang SY, Shui XJ. Experimental study of Love-wave immunosensors based on ZnO/LiTaO(3) structures. Ultrasonics. 2009 Oct 9; [Epub ahead of print] PMID: 19880154
• Zhou FW, Jin Y, Matta SG, Xu M, Zhou FM. An ultra-short dopamine pathway regulates basal ganglia output. J Neurosci. 2009 Aug 19;29(33):10424-35. PMID: 19692618
• Zhang T, Zhang L, Liang Y, Siapas AG, Zhou FM, Dani JA. Dopamine signaling differences in the nucleus accumbens and dorsal striatum exploited by nicotine. J Neurosci. 2009 Apr 1;29(13):4035-43. PMID: 19339599
• Zhou FW, Matta SG, Zhou FM. Constitutively active TRPC3 channels regulate basal ganglia output neurons. J Neurosci. 2008 Jan 9;28(2):473-82. PMID: 18184790
• Chen R, Tilley MR, Wei H, Zhou F, Zhou FM, Ching S, Quan N, Stephens RL, Hill ER, Nottoli T, Han DD, Gu HH. Abolished cocaine reward in mice with a cocaine-insensitive dopamine transporter. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9333-8. Epub 2006 Jun 5. PMID: 16754872
• Zhou FW, Xu JJ, Zhao Y, LeDoux MS, Zhou FM. Opposite functions of histamine H1 and H2 receptors and H3 receptor in substantia nigra pars reticulata. J Neurophysiol. 2006 Sep;96(3):1581-91. Epub 2006 May 31. PMID: 16738217

view complete list of references (pubmed link)