HONG-WEI DONG, Ph.D.

Assistant Professor

Department of Anatomy and Neurobiology

The University of Tennessee College of Medicine

Address

The University of Tennessee Health Science Center

855 Monroe Avenue, Suite 515

Memphis, TN 38163

Tel: (901) 448-1226; Fax: (901) 448-7193;

Education

Ph.D. Institution: Department of Neurobiology, Health Research Science Center, Peking University, Beijing, China

Postdoctoral: Washington University in St Louis, Department of Anatomy and Neurobiology; St Louis University, Department of Physiology and Pharmacology

Research Interests

Functional neural circuits in the brain involve a network of connected neurons, which process input and output information. The neural activity would be determined by the balance of synaptic excitation and inhibition. Any manipulations that shift the balance will change the output of the circuit. My research goal is to understand how the balance of excitation and inhibition within neuronal circuits is achieved, how it develops with experience, and how it changes in response to exogenous manipulations. I am currently investigating how various neurons interact and integrate chemical sensory information in the olfactory bulb circuits by employing neuroanatomical and neurophysiological approaches in brain slices.

Recent Publications

• Dong HW, Hayar A, Callaway J, Yang XH, Nai Q, Ennis M. Group I mGluR activation enhances Ca(2+)-dependent nonselective cation currents and rhythmic bursting in main olfactory bulb external tufted cells. J Neurosci. 2009 Sep 23;29(38):11943-53. PMID: 19776280
• Dong HW, Heinbockel T, Hamilton KA, Hayar A, Ennis M. Metabotropic glutamate receptors and dendrodendritic synapses in the main olfactory bulb. Ann N Y Acad Sci. 2009 Jul;1170:224-38. PMID: 19686141
• Nai Q, Dong HW, Hayar A, Linster C, Ennis M. Noradrenergic regulation of GABAergic inhibition of main olfactory bulb mitral cells varies as a function of concentration and receptor subtype. J Neurophysiol. 2009 May;101(5):2472-84. Epub 2009 Mar 11. PMID: 19279145
• Han HY, Lin JJ, Zhao QP, Dong H, Jiang LL, Wang X, Han JF, Huang B. [Construction of subtractive cDNA libraries of the sporogony stage of Eimeria tenella by suppression subtractive hybridization] Sheng Wu Gong Cheng Xue Bao. 2007 Nov;23(6):1005-10. Chinese. PMID: 18257227
• Yang YQ, Zhang LJ, Dong H, Jiang CL, Zhu ZG, Wu JX, Wu YL, Han JS, Xiao HS, Gao HJ, Zhang QH. Upregulated expression of S100A6 in human gastric cancer. J Dig Dis. 2007 Nov;8(4):186-93. PMID: 17970874
• Dong HW, Hayar A, Ennis M. Activation of group I metabotropic glutamate receptors on main olfactory bulb granule cells and periglomerular cells enhances synaptic inhibition of mitral cells. J Neurosci. 2007 May 23;27(21):5654-63. PMID: 17522310

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