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HITOSHI KITA, Ph.D.
- Professor
- Department of Anatomy and Neurobiology
- The University of Tennessee College of Medicine
Address
- The University of Tennessee Health Science Center
- 855 Monroe Avenue, Suite 515
- Memphis, TN 38163
- Tel: (901) 448-5234; Fax: (901) 448-7193;
- Lab: 516 Wittenborg Anatomy Building
Education
- Ph.D. Institution: Kyushu University, Department of Physiology
- Postdoctoral: Kyushu University, Department of Physiology
Research Interests
The study in my laboratory is to obtain precise descriptions of the function of the basal ganglia, including the neostriatum (STR), the subthalamic nucleus (STH), the substantia nigra (SN), and the globus pallidus (GP). Questions of interest are: 1) What are the membrane properties of STR, STH, SN and GP neurons? 2) What is the mode of action of STH inputs to GP and SN, and what are the neurotransmitters of these inputs? 3) What is the mode of action of GP inputs to STH and SN, and what neurotransmitter is involved? 4) What is the mode of action of SN inputs to STH and the neurotransmitter? 5) What are the morphological features of STH, GP and SN neurons, STH efferents to GP and SN, and GP and SN efferents to STH?
The physiological questions are addressed using intracellular recordings and neuropharmacological manipulations in both in vivo and in vitro slice preparations. The anatomical questions are addressed with light and electron microscope analysis of intracellularly labeled neurons, immunohistochemistry of neurotransmitter containing neurons and terminals, and the use of neurotracers to identify nerve elements.
Recent Publications
- Hashimoto K, Kita H.
Serotonin activates presynaptic and postsynaptic receptors in rat globus
pallidus.
J Neurophysiol. 2008 Apr;99(4):1723-32. Epub 2008 Jan 30.
PMID: 18234984
- Kita H.
Globus pallidus external segment.
Prog Brain Res. 2007;160:111-33. Review.
PMID: 17499111
- Kaneda K, Kita T, Kita H.
Repetitive activation of glutamatergic inputs evokes a long-lasting excitation
in rat globus pallidus neurons in vitro.
J Neurophysiol. 2007 Jan;97(1):121-33.
PMID: 17228082
- Kita H, Chiken S, Tachibana Y, Nambu A.
Serotonin modulates pallidal neuronal activity in the awake monkey.
J Neurosci. 2007 Jan 3;27(1):75-83.
PMID: 17202474
- Kita H, Chiken S, Tachibana Y, Nambu A.
Origins of GABA(A) and GABA(B) receptor-mediated responses of globus pallidus
induced after stimulation of the putamen in the monkey.
J Neurosci. 2006 Jun 14;26(24):6554-62.
PMID: 16775143
- Hashimoto K, Kita H.
Slow oscillatory activity of rat globus pallidus neurons in vitro.
Eur J Neurosci. 2006 Jan;23(2):443-53.
PMID: 16420451
view complete list of references (pubmed link)
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