MICHAEL JACEWICZ, M.D.

Professor

Department of Neurology

Department of Anatomy and Neurobiology

The University of Tennessee College of Medicine

Address

The University of Tennessee Health Science Center

415 Link Building

855 Monroe Avenue

Memphis, TN 38163

Tel: (901) 448-5219; Fax: (901) 448-7440;

Education

M.D. Institution: Case Western Reserve University, School of Medicine

Research Interests

Mechanisms of ischemic brain injury, recovery, and blood flow regulation are of major interest in this laboratory. Following middle cerebral artery occlusion in the rat, changes in cortical gene expression and electrophysiologic function are correlated to ischemia severity, duration, and histologic outcome. Techniques include cerebral blood flow studies (autoradiographic and Laser Doppler), histopathology, image analysis, two-dimensional gel electrophoresis, in situ hybridization, measurement of DC potentials, and pharmacologic intervention. Clinical research includes the detection and quantification of arterial platelet-fibrin microemboli during coronary artery bypass grafting and their relationship to neurologic and neuropsychological outcome.

Links

Neurology - Michael Jacewicz

Recent Publications

• Kamiya T, Jacewicz M, Nowak TS Jr, Pulsinelli WA. Cerebral blood flow thresholds for mRNA synthesis after focal ischemia and the effect of MK-801. Stroke. 2005 Nov;36(11):2463-7. Epub 2005 Oct 13. PMID: 16224091
• Huang Z, Jacewicz M, Pfeiffer RF. Anticardiolipin antibody in vascular parkinsonism. Mov Disord. 2002 Sep;17(5):992-7. PMID: 12360548
• Ruckenstein MJ, McKown KM, Jacewicz M. Unusual and instructive case of immune-mediated inner ear disease associated with central nervous system vasculitis. Otolaryngol Head Neck Surg. 2000 Jan;122(1):109-11. No abstract available. PMID: 10629494
• Pulsinelli WA, Jacewicz M, Levy DE, Petito CK, Plum F. Ischemic brain injury and the therapeutic window. Ann N Y Acad Sci. 1997 Dec 19;835:187-93. Review. No abstract available. PMID: 9616773
• Jacewicz M. Ischemia-modulating and neuroprotective drugs. Tenn Med. 1997 Oct;90(10):411-3. No abstract available. PMID: 9323907
• Nowak TS Jr, Jacewicz M. The heat shock/stress response in focal cerebral ischemia. Brain Pathol. 1994 Jan;4(1):67-76. Review. PMID: 8025704

view complete list of references (pubmed link)