RONALD F. PFEIFFER, M.D.

Professor

Department of Neurology

The University of Tennessee College of Medicine

Address

The University of Tennessee Health Science Center

855 Monroe Avenue, Room 415

Memphis, TN 38163

Tel: (901) 448-6811; Fax: (901) 448-7440;

Education

M.D. Institution: University of Nebraska Medical Center

Postdoctoral: Walter Reed Army Medical Center

Research Interests

The primary focus of my research is on Parkinson's disease. Clinical trials of experimental antiparkinson medications are an ongoing facet of the research program. Gastrointestinal dysfunction in Parkinson's disease also has become a major focus of my research interest. Characterization of the clinical profile of GI dysfunction in Parkinson's disease has been undertaken and experimental treatment protocols also developed. More recently, collaborative studies investigating the underlying pathophysiology of GI dysfunction in Parkinson's disease have been instituted.

We are also investigating, via primary cell culture techniques, possible toxic factors to dopamine neurons along with studies of cytoskeletal changes that may have relevance to Lewy body formation.

Links

Neurology - Ronald F. Pfeiffer

Recent Publications

• Bloomer RJ, Schilling BK, Karlage RE, Ledoux MS, Pfeiffer RF, Callegari J. Effect of resistance training on blood oxidative stress in Parkinson disease. Med Sci Sports Exerc. 2008 Aug;40(8):1385-9. PMID: 18614956
• Wszolek ZK, Vieregge P, Uitti RJ, Gasser T, Yasuhara O, McGeer P, Berry K, Calne DB, Vingerhoets FJ, Klein C, Pfeiffer RF. German-Canadian family (family A) with parkinsonism, amyotrophy, and dementia - Longitudinal observations. Parkinsonism Relat Disord. 1997 Nov;3(3):125-39. PMID: 18591067
• Pfeiffer RF. Wilson's Disease. Semin Neurol. 2007 Apr;27(2):123-32. Review. PMID: 17390257
• Pfeiffer RF, Gutmann L, Hull KL Jr, Bottini PB, Sherry JH; APO302 Study Investigators. Continued efficacy and safety of subcutaneous apomorphine in patients with advanced Parkinson's disease. Parkinsonism Relat Disord. 2007 Mar;13(2):93-100. Epub 2006 Oct 18. PMID: 17055329
• Pfeiffer RF. A promising new technology for Parkinson's disease. Neurology. 2005 Jul 26;65(2 Suppl 1):S6-10. Review. No abstract available. PMID: 16030292
• Nausieda PA, Pfeiffer RF, Tagliati M, Kastenholz KV, DeRoche C, Slevin JT. A multicenter, open-label, sequential study comparing preferences for carbidopa-levodopa orally disintegrating tablets and conventional tablets in subjects with Parkinson's disease. Clin Ther. 2005 Jan;27(1):58-63. Erratum in: Clin Ther. 2005 Mar;27(3):360. PMID: 15763606

view complete list of references (pubmed link)