RYOICHI TERUYAMA, Ph.D.

Assistant Professor

Department of Anatomy and Neurobiology

The University of Tennessee College of Medicine

Address

The University of Tennessee Health Science Center

855 Monroe Avenue, Suite 515

Memphis, TN 38163

Tel: (901) 448-5995;

Lab: 212 Wittenborg Anatomy Building

Research Interests

The neurohypophysial hormones oxytocin and vasopressin are synthesized in magnocellular neurons located within the hypothalamus, and play important roles in lactation and cardiovascular homeostasis. My research interest is focused on understanding how these neuroendocrine cells respond to physiological demands of these hormones. Specifically, we examine the effects of lactation and dietary salt-intake on the firing patterns of these neurons that ultimately define the amount and rate of these hormones into the general circulation. To elucidate the cellular responses, we employ integrative approach combining electrophysiology, immunocytochemistry, and single cell RT-PCR.

Recent Publications

• Teruyama R, Lipschitz DL, Wang L, Ramoz GR, Crowley WR, Bealer SL, Armstrong WE. Central blockade of oxytocin receptors during mid-late gestation reduces amplitude of slow afterhyperpolarization in supraoptic oxytocin neurons. Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1167-71. Epub 2008 Sep 23. PMID: 18812459
• Teruyama R, Armstrong WE. Calcium-dependent fast depolarizing afterpotentials in vasopressin neurons in the rat supraoptic nucleus. J Neurophysiol. 2007 Nov;98(5):2612-21. Epub 2007 Aug 22. PMID: 17715195
• Armstrong WE, Rubrum A, Teruyama R, Bond CT, Adelman JP. Immunocytochemical localization of small-conductance, calcium-dependent potassium channels in astrocytes of the rat supraoptic nucleus. J Comp Neurol. 2005 Oct 24;491(3):175-85. PMID: 16134141
• Teruyama R, Armstrong WE. Enhancement of calcium-dependent afterpotentials in oxytocin neurons of the rat supraoptic nucleus during lactation. J Physiol. 2005 Jul 15;566(Pt 2):505-18. Epub 2005 May 5. PMID: 15878948
• Shevchenko T, Teruyama R, Armstrong WE. High-threshold, Kv3-like potassium currents in magnocellular neurosecretory neurons and their role in spike repolarization. J Neurophysiol. 2004 Nov;92(5):3043-55. Epub 2004 Jul 7. PMID: 15240761
• Roper P, Callaway J, Shevchenko T, Teruyama R, Armstrong W. AHP's, HAP's and DAP's: how potassium currents regulate the excitability of rat supraoptic neurones. J Comput Neurosci. 2003 Nov-Dec;15(3):367-89. PMID: 14618071

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