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College of Medicine

The Neuroscience Institute

Research Resources

Mutant, transgenic, knockout mouse lines

GFP mouse lines

Matt Ennis lab

GAD-67 GFP (from Gabor Szabo): maintained by breeding heterozygous mice.
Not here yet but will be shipped to my lab in the next month, and then I will breed.

Proprietary: need permission from creator to use, who requests authorship as a condition of use.

Tony Reiner lab

We maintain a colony of D2-EGFP GENSAT transgenic mice. These mice have EGFP expression in D2-expressing neurons in the nervous system.

Tonia Rex lab

Betatubulin-EYFP mice on the FVB (rd1) background (these are from E.Geisert and D. Goldowitz’s colony)

M/LconeOpsin-EGFP mice on the C57Bl/6 background.

Fu-Ming Zhou lab

ChAT-GFP (Stock no.: 007902, strain name: B6.Cg-Tg(RP23-268L19-EGFP)2Mik/J, from Jackson). 2 breeding pairs just arrived on 9/15/2008.

GAD67-GFP (stock number: 007677, strain name: CB6-Tg(Gad1-EGFP)G42Zjh/J, from Jackson). Order still on waiting list.

Mutant, transgenic, knockout mouse lines

Andrea Elberger lab

two lines of NMDA-NR1 receptor deletion mice

Matt Ennis lab

mGluR1 knockout: maintained by breeding heterozygous mice.
B-galactosidase replaces mGluR1 gene, so B-gal histochemistry or immunocytochemistry can be used to determine cells that express mGluR1.

mGluR5 knockout: maintained by breeding homozygous mice.

Mark LeDoux lab

SGCE-KO mice

torsinA transgenic

Mike McDonald lab

APP/PSEN1 and 5xFAD transgenics (from Jackson)

GD3 synthase knockout (available cryopreserved for ~$1800 but I think I can share under the MTA).

Huaibin Cai’s DJ-1 model of Parkinson’s disease, possibly too old to breed. They’re freely available from Huaibin but there’s a waiting list for young ones

Tony Reiner lab

R6/2 Huntington’s disease transgenic mice

YAC128 HD transgenic mice.

Tonia Rex lab

rds mice on C3H and Balb/c backgrounds

rd7 mice on C57Bl/6 background

VMD2.rtTA and Ops.rtTA mice (I think this are on C57Bl/6 background)

Fu-Ming Zhou lab

Dopamine D1 KO from Ming Xu of University of Chicago, under MTA and permission is required.

Dopamine D5 KO from David Sibly of NINDS. Permission is required.